JUM
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Order Full text via Infotrieve
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Otis, S. M.
Right arrow Articles by Ringelstein, E. B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Otis, S. M.
Right arrow Articles by Ringelstein, E. B.

Journal of Ultrasound in Medicine, Vol 8, Issue 3 143-148, Copyright © 1989 by American Institute of Ultrasound in Medicine

JOURNAL ARTICLE

Relationship of cerebral blood flow regulation to acute mountain sickness

S. M. Otis, M. E. Rossman, P. A. Schneider, M. P. Rush and E. B. Ringelstein
Division of Neurology, Scripps Clinic and Research Foundation, La Jolla, California 92037.

Acute mountain sickness (AMS) is a prevalent illness seen in humans exposed to high altitudes. An increase in cerebral blood flow as a result of cerebrovasodilatation is felt by many to be responsible for its occurrence. Using the recently developed transcranial Doppler (TCD), it has become possible to detect and quantify flow velocity in the large cerebral vessels. By this method, intracranial arterial blood flow velocities and vasodilatation were measured at high altitude and correlated with clinical symptoms. Mean middle cerebral artery velocity (MCA-V) showed a significant increase from 55 +/- 7 cm/s at sea level to 71 +/- 13 cm/s at 13,500 feet. The pulsatility index (PI) and vasomotor reactivity (VMR) both decreased (.71 +/- .11 at sea level to .53 +/- .12 at 13,500 and 45 +/- 17% sea level to 23 +/- 15% at 8,000 feet, respectively). These preliminary studies indicated that TCD technique is a viable tool for measurement of cerebral blood flow velocities and cerebral arterial vasodilatation at altitude.


This article has been cited by other articles:


Home page
 J. Physiol.Home page
L. J Norcliffe, M Rivera-Ch, V. E Claydon, J. P Moore, F Leon-Velarde, O Appenzeller, and R Hainsworth
Cerebrovascular responses to hypoxia and hypocapnia in high-altitude dwellers
J. Physiol., July 1, 2005; 566(1): 287 - 294.
[Abstract] [Full Text] [PDF]

Home page
 StrokeHome page
A. Van Osta, J.-J. Moraine, C. Melot, H. Mairbaurl, M. Maggiorini, and R. Naeije
Effects of High Altitude Exposure on Cerebral Hemodynamics in Normal Subjects
Stroke, March 1, 2005; 36(3): 557 - 560.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
J. C. Kolb, P. N. Ainslie, K. Ide, and M. J. Poulin
Effects of five consecutive nocturnal hypoxic exposures on the cerebrovascular responses to acute hypoxia and hypercapnia in humans
J Appl Physiol, May 1, 2004; 96(5): 1745 - 1754.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Biol.Home page
R. C. Roach and P. H. Hackett
Frontiers of hypoxia research: acute mountain sickness
J. Exp. Biol., March 11, 2002; 204(18): 3161 - 3170.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
R. W. Baumgartner, I. Spyridopoulos, P. Bartsch, M. Maggiorini, and O. Oelz
Acute mountain sickness is not related to cerebral blood flow: a decompression chamber study
J Appl Physiol, May 1, 1999; 86(5): 1578 - 1582.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
G. F. A. Jansen, A. Krins, and B. Basnyat
Cerebral vasomotor reactivity at high altitude in humans
J Appl Physiol, February 1, 1999; 86(2): 681 - 686.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1989 by the American Institute of Ultrasound in Medicine.