JUM GE Healthcare
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Order Full text via Infotrieve
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by LaFollette, L.
Right arrow Articles by Golbus, M. S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by LaFollette, L.
Right arrow Articles by Golbus, M. S.

Journal of Ultrasound in Medicine, Vol 8, Issue 12 657-660, Copyright © 1989 by American Institute of Ultrasound in Medicine

JOURNAL ARTICLE

Fetal femur length to detect trisomy 21. A reappraisal

L. LaFollette, R. A. Filly, R. Anderson and M. S. Golbus
Department of Diagnostic Radiology, University of California, School of Medicine, San Francisco, 94143.

An association between short femur length (FL) relative to the biparietal diameter (BPD) measured in the second trimester and the Down syndrome recently has been reported by Benacerraf et al (1987). Fetuses meeting an easily calculated criterion were stated to have a high probability for trisomy 21. We compared the biometric data from a selected group of 229 normal second trimester fetuses with 30 fetuses of similar gestational age with karyotype-proven trisomy 21. We found a substantial difference in femur lengths of normal fetuses in our population compared to that reported by Benacerraf et al. The reason for the difference is unclear. Further, we were unable to demonstrate a statistically discernible deviation of measured versus predicted femur lengths in the Down syndrome cohort employing either the formula recommended by Benacerraf et al or a formula calculated from our normal cohort.


This article has been cited by other articles:


Home page
 JAMAHome page
R. Smith-Bindman, W. Hosmer, V. A. Feldstein, J. J. Deeks, and J. D. Goldberg
Second-Trimester Ultrasound to Detect Fetuses With Down Syndrome: A Meta-analysis
JAMA, February 28, 2001; 285(8): 1044 - 1055.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1989 by the American Institute of Ultrasound in Medicine.