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© 2009 by the American Institute of Ultrasound in Medicine
J Ultrasound Med 28:801-806 • 0278-4297

Case Series

Follicular Thyroid Carcinoma With an Eggshell Calcification

Report of 3 Cases

Sang Kwon Lee, MD and Byung Hak Rho, MD

Department of Radiology, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea.

Address correspondence to Sang Kwon Lee, MD, Department of Radiology, Dongsan Medical Center, Keimyung University School of Medicine, 194 Dongsan-dong, Jung-gu, Daegu 700-712, Korea. E-mail: sklee{at}dsmc.or.kr

Objective. The purpose of this series is to report 3 cases of follicular thyroid carcinoma with an eggshell calcification along with their imaging findings. Methods. Imaging findings on gray scale and power Doppler (PD) sonography (n = 3), computed tomography (CT; n = 3), and integrated fluorodeoxyglucose F 18 (18F-FDG) whole-body positron emission tomography (PET)/CT (n = 1) were assessed. Results. Of the 3 cases, two 75-year-old women had bone metastasis, and one 54-year-old woman had a thyroid incidentaloma on sonography. All 3 cases had a spherical mass with an interrupted eggshell calcification on gray scale sonography and CT; 2 revealed intranodular vascularity on PD sonography, and 1 showed intense hypermetabolism (maximum standardized uptake value, 7.9 g/mL) on integrated 18F-FDG whole-body PET/CT. Conclusions. Follicular carcinoma should be considered in the differential diagnosis of a thyroid nodule with an eggshell calcification.

Key Words: calcifications • follicular carcinoma • sonography • thyroid

Abbreviations: CT, computed tomography • FDG, fluorodeoxyglucose • FNAB, fine-needle aspiration biopsy • PD, power Doppler • PET, positron emission tomography • PTC, papillary thyroid carcinoma • SUVmax, maximum standardized uptake value

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