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© 2009 by the American Institute of Ultrasound in Medicine
J Ultrasound Med 28:765-776 • 0278-4297

Review Article

Biological Aspects and Clinical Importance of Ultrasound Therapy in Bone Healing

Özgür Erdogan, DDS, PhD and Emin Esen, DDS, PhD

Department of Dental Services, Diyarbakir Military Hospital, Diyarbakir, Turkey (Ö.E.); and Department of Oral and Maxillofacial Surgery, Cukurova University, Faculty of Dentistry, Adana, Turkey (E.E.).

Address correspondence to Özgür Erdogan, DDS, PhD, 100 Yil Mahallesi 85337, Sokak 4-7, 01360 Seyhan-Adana, Turkey. E-mail: ozgerdogan{at}yahoo.com

Objectives. The purpose of this study was to review past and recent literature findings regarding the effects of ultrasound therapy on bone healing and its clinical efficacy in medical and dental interventions. Methods. A literature review was conducted on the effects of ultrasound therapy on bone healing. The studies regarding clinical applications in long bones and maxillofacial bones were evaluated separately from each other. Results. The effects of therapeutic ultrasound on bone healing have been studied for half a century. Numerous clinical and experimental studies have addressed this relationship, and many of them have shown positive correlations. Although several theories have been proposed to explain the mechanism of action, the exact mechanism has not been fully understood. Conclusions. Therapeutic ultrasound therapy in clinical settings is a noninvasive application and has no serious complications or side effects. It may be an acceptable treatment of choice in many types of clinical procedures involving maxillofacial bones.

Key Words: bone healing • bone remodeling • fracture • low-intensity ultrasound • maxillofacial surgery • orthopedic surgery • therapeutic ultrasound

Abbreviations: BMU, basic multicellular unit • LIPU, low-intensity pulsed ultrasound

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Copyright © 2009 by the American Institute of Ultrasound in Medicine.