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© 2009 by the American Institute of Ultrasound in Medicine
J Ultrasound Med 28:603-608 • 0278-4297

Utility of Fetal Echocardiography After Normal Cardiac Imaging Findings on Detailed Fetal Anatomic Ultrasonography

Roman S. Starikov, MD, Fadi A. Bsat, MD, Alexander B. Knee, MS, Anna E. Tsirka, MD, Yvonne Paris, MD and Glenn R. Markenson, MD

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology (R.S.S., F.A.B., A.B.K., G.R.M.), and Division of Pediatric Cardiology, Department of Pediatrics (A.E.T., Y.P.), Baystate Medical Center, Tufts University School of Medicine, Springfield, Massachusetts USA.

Address correspondence to Roman Starikov, MD, Department of Obstetrics and Gynecology, Baystate Medical Center, 759 Chestnut St, Springfield, MA 01199-0001 USA., E-mail: roman.starikov{at}bhs.org

Objective. The purpose of this study was to assess the utility of fetal echocardiography (FE) after normal fetal cardiac imaging findings during detailed fetal anatomic ultrasonography (FAU). Methods. We conducted a retrospective cohort review of obstetric ultrasonographic studies from November 2001 through July 2005. We identified women with a singleton gestation with increased risk for congenital heart disease who received FAU performed by a maternal-fetal medicine specialist at 16 to 20 weeks’ gestation with subsequent FE. These records were compared with newborn outcomes. Results. Of 789 pregnancies that had FAU and FE, 481 had satisfactory cardiac imaging. Of those, only 1 fetus had abnormal FE findings. After delivery, 4 of the 480 neonates with normal FAU and FE findings had a diagnosis of a heart defect. Conclusions. Fetal echocardiography does not substantially increase the detection rate of major cardiac anomalies after normal findings on detailed FAU performed by a maternal-fetal medicine specialist.

Key Words: congenital heart disease • detailed fetal anatomic ultrasonography • fetal echocardiography

Abbreviations: CHD, congenital heart disease • CI, confidence interval • FAU, fetal anatomic ultrasonography • FE, fetal echocardiography • ICD-9, International Classification of Diseases, Ninth Revision • NPV, negative predictive value • PPV, positive predictive value • VSD, ventricular septal defect







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