JUM
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Google Scholar
Right arrow Articles by Ilves, P.
Right arrow Articles by Veinla, M.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ilves, P.
Right arrow Articles by Veinla, M.
© 2008 by the American Institute of Ultrasound in Medicine
J Ultrasound Med 27:199-207 • 0278-4297

Developmental Changes in Cerebral and Visceral Blood Flow Velocity in Healthy Neonates and Infants

Pilvi Ilves, MD, PhD, Mare Lintrop, MD, MSc, Inga Talvik, MD, Külli Muug, MD, Karin Asser, MD and Maie Veinla, MD

Radiology Service (P.I., M.L., K.A.) and Children’s Clinic (I.T., K.M., M.V.), Tartu University Hospital, Tartu, Estonia; and Department of Hematology and Oncology, University of Tartu, Tartu, Estonia (P.I., M.L.).

Address correspondence to Pilvi Ilves, MD, PhD, Department of Hematology and Oncology, University of Tartu, Lunini 6, 51014 Tartu, Estonia. E-mail pilvi.ilves{at}kliinikum.ee

Objective. The purpose of this study was to evaluate the changes in Doppler blood flow velocity (BFV) in cerebral and visceral arteries during infancy. Methods. The BFV was measured in 37 healthy term neonates in the anterior cerebral artery (ACA), middle cerebral artery (MCA), basilar artery, internal carotid artery (ICA), celiac artery (CA), superior mesenteric artery (SMA), and renal artery (RA). Results. The mean BFV increased and the resistive index decreased (P < .05) in all cerebral arteries, SMA, and CA by the age of 12 to 23.9 hours and in the RA by the age of 24 to 35.9 hours compared with 2 to 11.9 hours. A further significant increase (P < .05) of the mean BFV occurred in all arteries except the ICA and CA by the age of 72 to 120 hours compared with 12 to 23.9 hours. By the age of 21 to 59 days, the mean BVF doubled in all investigated arteries compared with 2 to 11.9 hours, with a further significant increase (P < .05) by the age of 150 to 240 days in cerebral and renal arteries. There was no correlation between the mean blood pressure (BP) and mean BFV in the ACA and MCA. However, there was a positive correlation (r ≥ 0.5; P < .05) between the BP and BFV in the RA and SMA at the age of 12 to 23.9 hours. Conclusions. A significant increase in the cerebral and visceral BFV occurs normally throughout infancy, with the visceral BFV affected by BP changes during the first day of life.

Key Words: cerebral blood flow velocity • neonate • sonography • visceral blood flow velocity

Abbreviations: ACA, anterior cerebral artery • BA, basilar artery • BFV, blood flow velocity • BP, blood pressure • CA, celiac artery • CI, confidence interval • ICA, internal carotid artery • MCA, middle cerebral artery • RA, renal artery • RI, resistive index • SMA, superior mesenteric artery • TAMV, time of the maximum velocity envelope curve • TAV, time-averaged velocity • Vd, end-diastolic flow velocity • Vs, systolic flow velocity

HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2008 by the American Institute of Ultrasound in Medicine.