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© 2008 by the American Institute of Ultrasound in Medicine
J Ultrasound Med 27:1-6 • 0278-4297

Intraobserver and Interobserver Reproducibility of 3-Dimensional Power Doppler Vascular Indices in Assessment of Solid and Cystic-Solid Adnexal Masses

Juan Luis Alcázar, MD, David Rodriguez, MD, Pedro Royo, MD, Rosendo Galván, MD, Silvia Ajossa, MD and Stefano Guerriero, MD

Department of Obstetrics and Gynecology, Clinica Universitaria de Navarra, University of Navarra, Pamplona, Spain (J.L.A., P.R., R.G.); Department of Obstetrics and Gynecology, Hospital Sant Joan de Déu, University of Barcelona, Barcelona, Spain (D.R.); and Department of Obstetrics and Gynecology, Ospedale San Giovanni di Dio, University of Cagliari, Cagliari, Italy (S.A., S.G.).

Address correspondence to Juan Luis Alcázar, MD, Department of Obstetrics and Gynecology, Clinica Universitaria de Navarra, Avenida Pio XII 36, 31008 Pamplona, Spain. E-mail: jlalcazar{at}unav.es

Objective. The purpose of this study was to assess the intraobserver and interobserver reproducibility of 3-dimensional (3D) power Doppler angiography–derived vascular indices in evaluation of vascularized solid and cystic-solid adnexal masses. Methods. Stored 3D power Doppler angiographic volume data from 12 consecutive women with a diagnosis of a complex adnexal mass (6 cystic-solid and 6 solid) evaluated and treated at our institution were retrieved from our database for analysis. Two examiners performed the calculations blinded to each other. Calculations were performed offline in a computer using Virtual Organ Computer-Aided Analysis software (plane A, 9° rotation step) to assess volume and vascularization (vascularization index, flow index, and vascularization-flow index) from solid areas within the tumor. In all cases, a definitive histologic diagnosis was obtained. Intraobserver and interobserver reproducibility was assessed by calculating the intraclass and interclass correlation coefficients for each index. Results. All tumors proved to be malignant after surgical removal. Intraobserver reproducibility for both examiners and interobserver reproducibility were high for all indices (interclass correlation coefficient > 0.95). Conclusions. Three-dimensional power Doppler angiography is a reproducible technique for offline assessment of stored 3D volume data of vascularized adnexal masses.

Key Words: power Doppler sonography • reproducibility • 3-dimensional sonography

Abbreviations: FI, flow index • 3D, 3-dimensional • 3D-PDA, 3-dimensional power Doppler angiography • VFI, vascularization-flow index • VI, vascularization index • VOCAL, Virtual Organ Computer-Aided Analysis

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Copyright © 2008 by the American Institute of Ultrasound in Medicine.