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© 2007 by the American Institute of Ultrasound in Medicine
J Ultrasound Med 26:825-828 • 0278-4297

The Value of Repeated Evaluation After Initial Failed Nuchal Translucency Measurement

Joseph R. Wax, MD, Michael G. Pinette, MD, Angelina Cartin and Jacquelyn Blackstone, DO

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Maine Medical Center, Portland, Maine USA.

Address correspondence to Joseph R. Wax, MD, MMC Ob/Gyn Associates, 887 Congress St, Suite 200, Portland, ME 04102 USA. E-mail: waxj{at}mmc.org

Objective. The purpose of this study was to assess the value of reattempting the nuchal translucency (NT) measurement after an initial failure. Methods. Women undergoing NT measurements by NT-certified sonographers within a combined screening program over an 18-month period were categorized as "desiring" screening (all women), "eligible" (live fetus with crown-rump length of 45–84 mm), and "defaulters" (failed to keep a visit after a failed NT measurement attempt). If the NT measurement was unobtainable, patients with live fetuses and a crown-rump length of less than 84 mm were offered reexamination. Results. Nuchal translucency measurement success rates at the initial visit for those desiring (n = 837) and eligible (n = 767) were 73.3% and 80.0%, respectively. Composite NT measurement success rates for up to 3 visits were significantly greater than for only 1 visit for those desiring screening (84.8%; P < .0001), eligible for screening (86.6%; P = .0004), and not defaulting on follow-up (97.0%; P < .0001). The screen-positive rates were similar for 1 and up to 3 visits (10.4% and 11.0%). One additional (16.6%) aneuploidy was detected through a second visit. Conclusions. Reattempting NT measurements significantly increases the overall NT measurement success rate and detects additional aneuploidies at constant screen-positive and invasive prenatal diagnosis rates.

Key Words: Down syndrome • nuchal translucency • prenatal diagnosis

Abbreviations: CRL, crown-rump length • NT, nuchal translucency • TVUS, transvaginal ultrasonography







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