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by the American Institute of Ultrasound in Medicine J Ultrasound Med 26:1761-1765 0278-4297 Primary Thyroid LymphomaRole of Ultrasound-Guided Needle BiopsyDepartment of Diagnostic Radiology, Research Institute of Radiological Science (J.Y.K., E.-K.K., M.J.K., E.J.S., K.K.O., K.W.K.), and Department of Pathology (W.I.Y.), Yonsei University College of Medicine, Seoul, Korea; and Department of Diagnostic Radiology, Cha General Hospital, College of Medicine, Pochon Cha University, Seoul, Korea (K.H.K.). Address correspondence to Eun-Kyung Kim, MD, Department of Diagnostic Radiology, Yonsei University College of Medicine, 250 Seongsanno, 134 Sinchondong, Seodaemungu, Seoul 120–752, Korea., E-mail: ekkim{at}yumc.yonsei.ac.kr
Objective. The purpose of this study was to describe the sonographic findings of primary thyroid lymphoma and evaluate the role of ultrasound-guided biopsy in diagnosing thyroid lymphoma. Methods. This study included 6 patients (age range, 56–72 years; mean, 62.5 years). We searched the database of our institution and retrospectively collected data on the thyroid lymphomas that were confirmed pathologically. All of the sonograms and medical records were reviewed retrospectively. Results. All 6 patients had an enlarged neck mass and underwent ultrasound-guided fine-needle aspiration biopsy. The most notable sonographic feature of primary thyroid lymphoma was a marked hypoechoic mass compared with the residual thyroid tissue. Among the 6 patients with a diagnosis of thyroid lymphoma, 3 (50%) had a diagnosis of lymphoma by ultrasound-guided fine-needle aspiration biopsy. Final pathologic results were obtained by ultrasound-guided core needle biopsy (3/6 patients [50%]) or thyroidectomy (3/6 [50%]). Most patients with thyroid lymphoma (5/6 [83.3%]) were found to have diffuse large B-cell lymphoma and were treated with chemotherapy with or without radiotherapy. In 1 patient with follicular lymphoma, diagnosis and treatment were accomplished by total thyroidectomy. Conclusions. Our results show that ultrasound-guided core needle biopsy can be a safe and accurate method for diagnosing thyroid lymphoma and may be a suitable replacement for diagnostic thyroid surgery.
Key Words: lymphoma head and neck neoplasms thyroid biopsy thyroid neoplasm ultrasound guidance Abbreviations: US-CNB, ultrasound-guided core needle biopsy US-FNAB, ultrasound-guided fine-needle aspiration biopsy This article has been cited by other articles:
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