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© 2007 by the American Institute of Ultrasound in Medicine
J Ultrasound Med 26:55-58 • 0278-4297

Sonographic Evaluation of the Endometrium in Patients With a History or an Appearance of Polycystic Ovarian Syndrome

Nagamani Peri, MD and Deborah Levine, MD

Department of Radiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts USA.

Address correspondence to Deborah Levine, MD, Department of Radiology, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215 USA. E-mail: dlevine{at}bidmc.harvard.edu

Objective. The purpose of this study was to assess the incidence and significance of a thick, cystic-appearing endometrium in association with a history or an ovarian appearance of polycystic ovarian syndrome. Methods. An Institutional Review Board–approved, retrospective medical record review of sonographic studies from January 1, 1998, to December 31, 2005, found 245 patients with clinical features, a characteristic sonographic appearance of the ovaries, hormonal abnormalities, or a history of polycystic ovarian syndrome. The sonographic thickness and appearance of the endometrium (homogeneous or heterogeneous) and histologic findings on biopsy were obtained. Results. Two hundred twenty-seven patients had a homogeneous endometrium in the range of 1 to 17 mm (mean ± SD, 6.4 ± 3.1 mm); 18 patients had a heterogeneous endometrium in the range of 4 to 23 mm (mean, 13.2 ± 5.6 mm). Of the 18 patients with a heterogeneous endometrium, 9 also had a sonographic finding of tiny cystic foci within the endometrium. Of these, 5 had endometrial biopsy, resulting in 2 cases of a proliferative endometrium and 1 case each of simple hyperplasia, hyperplasia with atypia, and scant tissue. No cases of hyperplasia were present in the patients with a homogeneous endometrium. Conclusions. A heterogeneous cystic endometrium is associated with the prolonged proliferative phase from chronic anovulation as well as endometrial hyperplasia.

Key Words: endometrium • hyperplasia • polycystic ovarian syndrome • polycystic ovaries • sonography

Abbreviations: PCOS, polycystic ovarian syndrome




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N. N. Mahajan, R. Singh, K. N. Mahajan, and D. Levine
Sonographic Evaluation of the Endometrium in Patients With a History or an Appearance of Polycystic Ovarian Syndrome * Reply
J. Ultrasound Med., June 1, 2007; 26(6): 862 - 862.
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