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© 2005 by the American Institute of Ultrasound in Medicine
J Ultrasound Med 24:1251-1259 • 0278-4297

Technical Advance

Vitreous Image Enhancement in an Ophthalmic Sonographic Imaging System Using Golay Coded Excitation

Kai Liu, MS, Qiyu Peng, PhD, Xueqiao Wang, MS and Shangkai Gao, MS

Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China (K.L., S.G.); Department of Urology, School of Medicine, Stanford University, Stanford, California USA (Q.P.); and Tianjin Suoer Electronics Co, Ltd, Tianjin, China (X.W.).

Address correspondence and reprint requests to Kai Liu, MS, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 10084, China. E-mail: liukai97{at}mails.tsinghua.edu.cn

Objective. The purpose of this study was to enhance the weak echoes of low reflective vitreous opacities on ophthalmic sonography. Methods. A simulation study on a vitreous enhancement algorithm based on coded excitation was performed, with the analysis of the transmit efficiency and motion effects. On the basis of the simulation results, we have implemented a 10-MHz B-mode experimental sonographic platform with coded excitation. In the experimental platform, a field programmable gated array is used to apply a real-time signal-processing and imaging algorithm. Results. A high-frequency ophthalmic sonographic imaging system based on Golay complementary sequence coded excitation is presented. The images of human eyes show appreciable improvement of the contrast resolution of low reflective vitreous opacities while suppressing the noise level. Conclusions. The images show the effectiveness of the vitreous enhancement algorithm and its potential clinical application.

Key Words: coded excitation • image enhancement • ophthalmic sonography • vitreous

Abbreviations: A/D, analog/digital • FPGA, field programmable gated array • RF, radio frequency • SNR, signal-noise ratio

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Copyright © 2005 by the American Institute of Ultrasound in Medicine.