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© 2003 by the American Institute of Ultrasound in Medicine
J Ultrasound Med 22:1363-1368 • 0278-4297

Case Series

Prenatal Diagnosis of Aneurysms of the Vein of Galen (Vena Magna Cerebri) With Conventional Sonography, Three-dimensional Sonography, and Magnetic Resonance Imaging

Report of 2 Cases

Franca A. Gerards, MD, Melanie A. J. Engels, MD, Frederik Barkhof, PhD, Frank A. M. van den Dungen, MD, R. Jeroen Vermeulen, PhD and John M. G. van Vugt, PhD

Departments of Obstetrics and Gynecology (F.A.G., M.A.J.E., J.M.G.v.V.), Radiology (F.B.), Child Neurology (R.J.V.), and Neonatology (F.A.M.v.d.D.), VU Medical Center, Amsterdam, the Netherlands. Manuscript accepted for publication June 5, 2003.

Address correspondence and reprint requests to Franca A. Gerards, MD, Department of Obstetrics and Gynecology, VU Medical Center, Room L-355, PO Box 7057, 1007 MB, Amsterdam, the Netherlands. E-mail: fa.gerards{at}vumc.nl.

Objective. To describe the cases of 2 fetuses with aneurysms of the vein of Galen diagnosed prenatally. Methods. The techniques used were conventional sonography, three-dimensional sonography, and ultrafast magnetic resonance imaging. On the basis of these imaging modalities, prognostic factors, such as drainage and secondary damage, were assessed. Results. The first fetus had good prognostic indices, and embolization after birth was successful. According to the prognostic factors, a poor neonatal outcome was predicted for the second fetus. The neonate died soon after birth. Conclusions. Conventional sonography, color Doppler imaging, and magnetic resonance imaging appeared to be useful diagnostic tools. The prognostic factors can be useful in counseling patients and providing the best possible care after birth.

Key Words: aneurysmal malformations • prenatal magnetic resonance imaging • prognostic indices • sonographic diagnosis • three-dimensional color power angiography • vein of Galen

Abbreviations: CPA, color power angiography • MRA, magnetic resonance angiography • MRI, magnetic resonance imaging • 3D, three-dimensional

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Copyright © 2003 by the American Institute of Ultrasound in Medicine.