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© 2002 by the American Institute of Ultrasound in Medicine
J Ultrasound Med 21:915-920 • 0278-4297


Case Series

Sirenomelia Sequence

First-Trimester Diagnosis With Both Two- and Three-dimensional Sonography

Ana Monteagudo, MD, Patricia Mayberry, RDMS, Andrei Rebarber, MD, Michael Paidas, MD and Ilan E. Timor-Tritsch, MD

Department of Obstetrics and Gynecology, Division of Obstetric and Gynecologic Ultrasound, New York University School of Medicine, New York, New York.

Address correspondence and reprint requests to Ana Monteagudo, MD, 530 First Ave, Room NB 9N26-A, New York, NY 10023.

Objective. To describe the sonographic findings of sirenomelia during the first trimester on both two-dimensional sonography with color Doppler imaging and three-dimensional sonography. Methods. Two cases of sirenomelia in primiparous patients with histories of infertility are described. The diagnosis was made on the basis of two-dimensional sonography, and three-dimensional sonography was used to further characterize the findings. Results. Both fetuses had size-date discrepancies, increased nuchal translucency, large intra-abdominal vessels, and 2-vessel umbilical cords. Both pregnancies were terminated by dilation and curettage after the patients viewed the three-dimensional pictures of the fetuses. Conclusions. During the first trimester of pregnancy, rare and lethal anomalies can be diagnosed with a high degree of confidence if a thorough, age-dependant anatomic survey of the fetus is performed.

Key Words: CRL, crown–rump length • D&C, dilation and curettage • 3D, three-dimensional • 2D, two-dimensional




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V. Nisenblat, Z. Leibovitz, B. Paz, I. Shapiro, S. Degani, and G. Ohel
Dizygotic Twin Pregnancy Discordant for Sirenomelia
J. Ultrasound Med., January 1, 2007; 26(1): 97 - 103.
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Copyright © 2002 by the American Institute of Ultrasound in Medicine.