JUM
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Liu, J. B.
Right arrow Articles by Forsberg, F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Liu, J. B.
Right arrow Articles by Forsberg, F.

Journal of Ultrasound in Medicine, Vol 20, Issue 5 517-523, Copyright © 2001 by American Institute of Ultrasound in Medicine

JOURNAL ARTICLE

The role of contrast-enhanced sonography for radiofrequency ablation of liver tumors

J. B. Liu, B. B. Goldberg, D. A. Merton, N. M. Rawool, L. Needleman and F. Forsberg
Department of Radiology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 19107, USA.

OBJECTIVE: To assess the feasibility and usefulness of contrast-enhanced sonography for tumor detection and guidance of liver VX2 tumor ablation and to evaluate post radiofrequency ablation effectiveness. METHODS: VX2 tumors were implanted into the livers of 6 rabbits. Both conventional and harmonic gray scale and power Doppler imaging were performed with a commercially available scanner to evaluate the liver tumors before and after intravenous injection of a sonographic contrast agent before and after radiofrequency ablation. Contrast-enhanced imaging was used to detect the tumors before ablation, to guide needle insertion, and to measure the ablation sites after radiofrequency ablation. Pathologic examination was performed for comparison. RESULTS: Three tumors were seen without contrast enhancement, whereas 10 tumors (<1 cm) were detected with contrast enhancement. Intentionally, 2 tumors were completely ablated and 5 tumors were partially ablated. In 3 cases, incompletely ablated tumors could only be identified on contrast-enhanced Doppler imaging by enhancing the detection of residual tumor vascularity. There was excellent concordance between sonographic imaging and gross pathologic findings. CONCLUSIONS: Contrast-enhanced sonographic imaging appears useful for detection of liver tumors and for guiding and monitoring tumor ablation therapies.


This article has been cited by other articles:


Home page
 J Ultrasound MedHome page
S.-Y. Chiou, J.-B. Liu, and L. Needleman
Current Status of Sonographically Guided Radiofrequency Ablation Techniques
J. Ultrasound Med., April 1, 2007; 26(4): 487 - 499.
[Abstract] [Full Text] [PDF]

Home page
 Br. J. Radiol.Home page
H Maruyama, S Matsutani, H Saisho, Y Mine, N Kamiyama, T Hirata, and M Sasamata
Real-time blood-pool images of contrast enhanced ultrasound with Definity in the detection of tumour nodules in the liver
Br. J. Radiol., June 1, 2005; 78(930): 512 - 518.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Surg. Oncol.Home page
D. L. Stippel, H. G. Brochhagen, M. Arenja, J. Hunkemoller, A. H. Holscher, and K. T. E. Beckurts
Variability of Size and Shape of Necrosis Induced by Radiofrequency Ablation in Human Livers: A Volumetric Evaluation
Ann. Surg. Oncol., April 1, 2004; 11(4): 420 - 425.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Roentgenol.Home page
J. R. Leyendecker, G. D. Dodd III, G. A. Halff, V. A. McCoy, D. H. Napier, L. G. Hubbard, K. N. Chintapalli, S. Chopra, W. K. Washburn, R. M. Esterl, et al.
Sonographically Observed Echogenic Response During Intraoperative Radiofrequency Ablation of Cirrhotic Livers: Pathologic Correlation
Am. J. Roentgenol., May 1, 2002; 178(5): 1147 - 1151.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2001 by the American Institute of Ultrasound in Medicine.