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Journal of Ultrasound in Medicine, Vol 20, Issue 1 43-49, Copyright © 2001 by American Institute of Ultrasound in Medicine
The utility of ultrasonographically guided large-core needle biopsy: results from 500 consecutive breast biopsies
D. N. Smith, M. L. Rosenfield Darling, J. E. Meyer, C. M. Denison, D. I. Rose, S. Lester, A. Richardson, C. M. Kaelin, E. Rhei and R. L. Christian
Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.
Five hundred ultrasonographically guided large-core needle breast biopsies
of solid masses were performed in 446 women. Histopathologic results were
correlated with imaging findings. Ultrasonographically guided large-core
needle biopsy resulted in diagnosis of malignancy (n = 124) or severe
atypical ductal hyperplasia (n = 4) in 128 lesions (26%). In the remaining
372 lesions (74%), ultrasonographically guided large-core needle biopsy
yielded benign pathologic results. Follow-up of more than 1 year (n = 225),
results of surgical excision (n = 50), or both were obtainable in 275 (74%)
of the benign lesions. No malignancies were discovered at surgical excision
or during follow-up of this group of benign lesions. There were no
complications related to large-core needle biopsy that required additional
treatment. Ultrasonographically guided large-core needle biopsy is a safe
and accurate method for evaluating breast lesions that require tissue
sampling.
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