Journal of Ultrasound in Medicine, Vol 15, Issue 8 557-562, Copyright © 1996 by American Institute of Ultrasound in Medicine
Role of Doppler ultrasonography in the prediction of pregnancy outcome in women with recurrent spontaneous abortion
M. C. Frates, P. M. Doubilet, D. L. Brown, C. B. Benson, D. N. DiSalvo, F. C. Laing, D. J. Berck and J. A. Hill
Department of Radiology, Brigham & Women's Hospital, Boston, MA 02115, USA.
We prospectively studied 96 patients with a history of recurrent
spontaneous abortion to determine whether the resistive index of the main
uterine artery or subchorionic vessels can allow prediction of pregnancy
outcome. The subchorionic RI declined progressively for a mean of 0.54 at 6
weeks to 0.42 at 13 weeks (P < 10(-8), F-test). No significant
difference was found in subchorionic RI values between outcomes for
liveborn infants versus loss. Uterine artery RI values also declined
significantly through the first trimester (P < 10(-8), F-test). Uterine
artery RI values tended to be lower in pregnancies ending in loss than in
successful gestations; however, there was too much overlap for this index
to be clinically useful. In conclusion, first trimester RI does not allow
prediction of pregnancy outcome in patients with recurrent abortion.