Journal of Ultrasound in Medicine, Vol 15, Issue 8 549-553, Copyright © 1996 by American Institute of Ultrasound in Medicine
Nonpalpable breast lesions: pathologic correlation of ultrasonographically guided fine-needle aspiration biopsy
A. O. Saarela, H. O. Kiviniemi, T. J. Rissanen and T. K. Paloneva
Department of Surgery, Oulu University Hospital, Finland.
To evaluate the usefulness of ultrasonographically guided fine-needle
aspiration biopsy in routine clinical use, we evaluated retrospectively all
of the 781 nonpalpable breast lesions operated on in the Oulu University
Hospital during the period 1986 to 1993. There were 86 patients with 90
nonpalpable breast lesions, of which samples were taken by
ultrasonographically guided fine-needle aspiration biopsy. Open wire-guided
surgical biopsy was obtained in all cases for a histologic diagnosis. Two
false-negative results and one insufficient cytologic sample occurred in
the 26 malignancies and one false-positive result and two insufficient
cytologic samples were found in the 73 benign breast lesions, giving
sensitivity, specificity, positive predictive value, negative predictive
value, and overall diagnostic accuracy values of 84%, 93%, 94%, 95%, and
90%, respectively. The calculations include the insufficient samples. We
conclude that ultrasonographically guided fine-needle aspiration biopsy is
a method comparable to mammographic and stereotactic fine-needle aspiration
biopsy methods.
