Journal of Ultrasound in Medicine, Vol 14, Issue 10 751-755, Copyright © 1995 by American Institute of Ultrasound in Medicine
Preovulatory sonographic uterine receptivity index (SURI): usefulness as an indicator of pregnancy in women undergoing assisted reproductive treatments
P. Serafini, J. Nelson, J. Batzofin and D. Olive
Huntington Reproductive Center, Pasadena, California, USA.
To evaluate the uterine component as a determinant variable in the
probability of establishing a pregnancy after assisted reproductive
treatments, we introduced a mathematical formula derived from standard
endovaginal uterine monitored color Doppler imaging parameters. We analyzed
102 cycles of ovarian stimulation with leuprolide acetate and exogenous
gonadotropins resulting in 52 clinical pregnancies by stepwise logistic
regression analysis. Sonographic endometrial pattern, thickness, diastolic
blood flow, and resistive index variables were transformed into categorical
variables and forced to yield a regression equation. Sonographic uterine
receptivity index was calculated as a summation of four times endometrial
pattern, five times resistive index, and two times diastolic blood flow.
This index yielded values for each patient in a range of 0 to 15. Scores
> or = 13 were associated with a successful outcome in 79.4% of the
patients, whereas scores between 8 and 12 were accompanied by 45.8%
pregnancy rates (P = 0.01), and scores < or = 7 had successful treatment
outcome in only 7.7% (P = 0.0001). The scores obtained by this mathematical
equation provide the ability to make reliable predictions about the outcome
of assisted reproductive treatments in women undergoing ovulation induction
with leuprolide acetate and human menopausal gonadotropins.
