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Journal of Ultrasound in Medicine, Vol 11, Issue 2 93-101, Copyright © 1992 by American Institute of Ultrasound in Medicine

JOURNAL ARTICLE

Conservation of receptor expression and phagocytic activity of murine macrophages exposed to various ultrasonic regimens in vitro

S. S. Prohaska, V. G. Rimer, M. A. Winters, R. C. Humphres, D. Tuse and P. D. Edmonds
Department of Cellular and Biochemical Technology, SRI International, Menlo Park, CA 94025.

Murine peritoneal macrophages insonated in vitro at 37 degrees C were assayed for impairment of adhesion to and spreading on glass coverslips, expressions of Fc gamma and C3b receptors, and phagocytosis. Insonation conditions were typical for exposures by B-mode imaging equipment and approximated the most severe exposures anticipated in use of pulsed Doppler equipment. In no case were the assay results for insonated samples significantly different from those for the sham-exposed controls.




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Copyright © 1992 by the American Institute of Ultrasound in Medicine.