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Journal of Ultrasound in Medicine, Vol 11, Issue 2 77-80, Copyright © 1992 by American Institute of Ultrasound in Medicine


JOURNAL ARTICLE

Umbilical and uterine Doppler velocimetry and prostaglandin levels in preeclampsia

L. Feinkind, D. Nanda and H. Minkoff
Department of Obstetrics and Gynecology, Health Science Center, Brooklyn, New York.

Eleven preterm patients with severe preeclampsia underwent Doppler velocimetry prior to cesarean section. Maternal venous blood and umbilical arterial and venous samples were collected for prostacyclin and thromboxane determination by radioimmunoassay. Umbilical artery pulsatility index correlated positively with umbilical artery thromboxane B2 levels (r = 0.76; P less than 0.05) and maternal thromboxane levels (r = 0.78; P less than 0.05). We conclude that the vasoactive action of thromboxane A2 may alter placental resistance.





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Copyright © 1992 by the American Institute of Ultrasound in Medicine.